Collagen Injections in Croatia

Collagen Injections in Croatia section, includes general infrmation about Collagen Injections Procedure, Collagen Injections Croatia Local News, Collagen Injections Croatia Surgeon Locator and other Collagen Injections related material.


Collagen Injections Procedure


As we grow older our face become more and more affected by the sun, gravity and use of expression muscles (chewing, smiling, etc). Deep tissues loose the ability to maintain a young look and expression marks appear on our faces. Collagen injections can help you fill the defects and regain younger appearance. It can be used to fill expression folds, sunken checks, scars and lips. This procedure is not sufficient to treat deep defects like multiple grooves around the mouse of heavy smokers. It can be done as isolated treatment or as a combination with laser, facelift and botox.

Collagen is a natural protein which gives support to various body parts, like skin, joints, bones and tendons. The injected formula is manufactured from a purified collagen from pigs. The purification process creates a material, which is similar to human collagen. The FDA approved it at 1981 for injections at different sites like face, neck, back and chest. It comes with different viscosity levels according to specific sites and the difference between the patients. The preparation already consists of analgesics; therefore there is no need for sedation. Especially sensitive patients can be treated with superficial spays to minimize the pain.

Before the treatment you must check allergy to collagen (it takes 3-4 weeks between the test and the injection). During the treatment collagen is being injected using a small needle along the wanted site. During the injections you may feel a burning sensation for a few minutes. Some of the formula consists of salt water, which gradually absorbs, therefore, at first, the site may look swollen. After the treatment it might be small hemorrhages or redness that usually disappear after 24 hours. With a few patients, especially those with bright skin color, the redness may last for a week. Every procedure has its ricks, those depend on patients anatomy, the healing processes and different physiologic responses. Most common complication is allergy to collagen. Others include infections, peeling of the skin, wounds and scaring. Those are relatively rare.

There is no need to bandage the site, and there are no limitations regarding food, drinking, make-up or sun exposure.

You must remember that the effect of the injection is only temporary. Due to their biological nature the injected materials disassemble by the body. The duration of the effect depends on genetics, age, skin quality, life style and the area being filled.

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More Croatia info...


  • Croatia By train

    The rail network connects all major Croatian cities, except Dubrovnik. There are direct lines from Austria, Switzerland, Germany, Hungary, Slovenia, Italy, Bosnia and Herzegovina, Serbia, Montenegro, and Greece. There are indirect lines from almost all other European countries.

    Tourists coming from or going to neighbouring countries should note the following EuroCity and InterCity railway lines:



  • Croatia Other destinations
    Plo?e
    Dugi Rat
    Omi?alj
    Omi? - coastal jewel built by the Pirots
    Ruskamen - most beautiful beaches on Adriatic.
    Njivice - Island of Krk
    Bol - island Bra?

    The United Nations Educational, Scientific and Cultural Organization (UNESCO) has included the following Croatian sites on its World Heritage List:


Plastic Surgery News...

  • Context  Gene expression profiling may be useful for prognostic and therapeutic strategies in breast carcinoma.

    Objectives  To demonstrate the value in integrating genomic information with clinical and pathological risk factors, to refine prognosis, and to improve therapeutic strategies for early stage breast cancer.

    Design, Setting, and Patients  Retrospective study of patients with early stage breast carcinoma who were candidates for adjuvant chemotherapy; 964 clinically annotated breast tumor samples (573 in the initial discovery set and 391 in the validation cohort) with corresponding microarray data were used. All patients were assigned relapse risk scores based on their respective clinicopathological features. Signatures representing oncogenic pathway activation and tumor biology/microenvironment status were applied to these samples to obtain patterns of deregulation that correspond with relapse risk scores to refine prognosis with the clinicopathological prognostic model alone. Predictors of chemotherapeutic response were also applied to further characterize clinically relevant heterogeneity in early stage breast cancer.

    Main Outcome Measures  Gene expression signatures and clinicopathological variables in early stage breast cancer to determine a refined estimation of relapse-free survival and sensitivity to chemotherapy.

    Results  In the initial data set of 573 patients, prognostically significant clusters representing patterns of oncogenic pathway activation and tumor biology/microenvironment states were identified within the low-risk (log-rank P = .004), intermediate-risk (log-rank P = .01), and high-risk (log-rank P = .003) model cohorts, representing clinically important genomic subphenotypes of breast cancer. As an example, in the low-risk cohort, of 6 prognostically significant clusters, patients in cluster 4 had an inferior relapse-free survival vs patients in cluster 1 (log-rank P = .004) and cluster 5 (log-rank P = .03). Median relapse-free survival for patients in cluster 4 was 16 months less than for patients in cluster 1 (95% CI, 7.5-24.5 months) and 19 months less than for patients in cluster 5 (95% CI, 10.5-27.5 months). Multivariate analyses confirmed the independent prognostic value of the genomic clusters (low risk, P = .05; high risk, P = .02). The reproducibility and validity of these patterns of pathway deregulation in predicting relapse risk was established using related but not identical clusters in the independent validation cohort. The prognostic clinicogenomic clusters also have unique sensitivity patterns to commonly used cytotoxic therapies.

    Conclusions  These results provide preliminary evidence that incorporation of gene expression signatures into clinical risk stratification can refine prognosis. Prospective studies are needed to determine the value of this approach for individualizing therapeutic strategies.


  • New study results released by the American Society for Dermatologic Surgery (ASDS) show the top procedures performed by dermasurgeons are skin cancer repair and reconstruction surgeries.

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